Isenzo esiphambili se-pharmacological yesithako esisebenzayo kwi-Fluconix-340, i-nitroxinil, i-fasciolicidal.Isenzo esibulalayo kwi-Fasciola hepatica sibonakaliswe kwi-vitro kunye ne-vivo kwizilwanyana zaselabhu, kunye neegusha kunye neenkomo.Indlela yokusebenza ibangelwa ukudibanisa i-phosphorylation ye-oxidative.Ikwasebenza ngokuchasene ne-triclabendazole-resistant
F. hepatica.
I-Fluconix-340 iboniswa kunyango lwe-fascioliasis (i-infestations ye-Fasciola hepatica ekhulile kwaye ekhulile) kwiinkomo kunye neegusha.Ikwasebenza, ngeqondo lethamo elicetyiswayo, ngokuchasene nohlaselo lwabantu abadala kunye nemibungu ye-Haemonchus contortus kwiinkomo neegusha kunye ne-Haemonchus placei, i-Oesophagostomum radiatum kunye ne-Bunostomum phlebotomum ezinkomeni.
Ungasebenzisi kwizilwanyana ezine-hypersensitivity eyaziwayo kwisithako esisebenzayo.
Musa ukusebenzisa kwizilwanyana ezivelisa ubisi ukuze zisetyenziswe ngabantu.
Musa ukudlula ithamo elichaziweyo.
Ukudumba okuncinci kubonwa ngamaxesha athile kwindawo yokutofa kwiinkomo.Ezi zinokuphetshwa ngokutofa idosi kwiindawo ezimbini ezahlukeneyo kunye nokuphulula kakuhle ukusasaza isisombululo.Akukho ziphumo zibi zilindelweyo xa izilwanyana (kuquka iimazi ezimithiyo kunye nee mazi) zinyangwa ngokwedosi eqhelekileyo.
Ngenaliti engaphantsi kwesikhumba.Qinisekisa ukuba inaliti ayingeni kwisihlunu esingaphantsi kwesikhumba.Nxiba iiglavu ezingenamanzi ukuze ugweme ukubola kunye nokucaphukisa ulusu.Idosi eqhelekileyo yi-10 mg nitroxinil ngekhilogram yobunzima bomzimba.
Iigusha: Lawula ngokwesikali samathamo silandelayo:
14 - 20 kg 0.5 ml 41 - 55 kg 1.5 ml
21 - 30 kg 0.75 ml 56 - 75 kg 2.0 ml
31 - 40 kg 1.0 ml> 75 kg 2.5 ml
Ekuqhambukeni kwe-fascioliasis igusha nganye emhlambini kufuneka itofwe ngokukhawuleza xa ubukho besifo buqondwa, ukuphinda unyango njengoko kuyimfuneko ngalo lonke ixesha xa uhlaselo lusenzeka, ngamaxesha angekho ngaphantsi kwenyanga enye.
Iinkomo: 1.5 ml yeFluconix-340 nge-50 kg yesisindo somzimba.
Zombini izilwanyana ezosulelekileyo nezithe wadibana nazo kufuneka zinyangwe, unyango luphinda-phindwa njengoko lubonwa luyimfuneko, nangona lungaxhaphakanga ngaphezu kwesinye ngenyanga.Iinkomo zobisi kufuneka zinyangwe xa zomile (ubuncinci iintsuku ezingama-28 phambi kokuba zizale).
Phawula: Ungasebenzisi kwizilwanyana ezivelisa ubisi ukuze zisetyenziswe ngabantu.
- Yenyama:
Iinkomo : iintsuku ezingama-60.
Iigusha : iintsuku ezingama-49.
Gcina ngaphantsi kwe 25ºC, kwindawo epholileyo neyomileyo, kwaye ukhusele ekukhanyeni.