Albendazole Bolus 2500mg
I-Albendazole yi-anthelmintic eyenziwe yeqela le-benzimidazole-derivatives esebenza ngokuchasene noluhlu olubanzi lweentshulube kwaye kwinqanaba ledosi ephezulu ngokuchasene nezigaba zabantu abadala ze-fluke.
Isenzo se-Pharmacological
I-Albendazole idityaniswe ne-eelworm's microtubule protein kwaye idlala indima.Emva kwe-albenzene edityaniswe ne-β-tubulin, inokuthintela ukudibanisa phakathi kwe-albenzene kunye ne-α tubulin kwi-microtubules.I-Microtubules sisiseko esisisiseko seeyunithi ezininzi zeeseli.Ubudlelwane be-Albendazole ne-nematodes tubulin buphezulu kakhulu kunobudlelwane be-mammalian tubulin, ngoko ke ubutyhefu kwi-mammalian buncinci.
Iimpawu
Iprophylaxis kunye nokunyangwa kweentshulube kumathole kunye neenkomo ezifana:
Iintshulube zesisu:IBunostomum, Cooperia, Chabertia, Haemonchus, Nematodirus, Oesophagostomum, Ostertagia, Strongyloides kunye neTrichostrongylus spp.
Lung worms:I-Dictyocaulus viviparus kunye ne-D. filaria.
Iintshulube zetapeworm:Monieza spp.
Umkhuhlane wesibindi:umntu omdala Fasciola hepatica.
I-Albendazole nayo inefuthe le-ovicidal.
Contra-izalathisi
Ulawulo kwiintsuku ezingama-45 zokuqala zokumitha.
Imiphumela
Ukusabela kwe-hypersensitivity.
Umthamo
Kulawulo lomlomo.
Ngeentshulube ezingqukuva, tapeworms:
Iinkomo / iinyathi / ihashe / iigusha / ibhokhwe: 5mg/kg ubunzima bomzimba
Inja / ikati: 10 ukuya 25mg / kg bodyweight
Ngeeflukes:
Iinkomo/inyathi: 10mg/kg ubunzima bomzimba
Igusha/ibhokhwe: 7.5mg/kg ubunzima bomzimba
Amathole kunye neenkomo: 1 bolus nge 300 kg.ubunzima bomzimba.
Ngomkhuhlane wesibindi:
1 bolus nge 250 kg.ubunzima bomzimba.
Isilumkiso
Gcina kwindawo ekude nabantwana.
Ixesha loQinisekiso
Iminyaka emi-3.
Amaxesha okurhoxa
- Yenyama :Iintsuku ezili-12.
- Ubisi :Iintsuku ezi-4.
Ugcino
Gcina kwindawo epholileyo, eyomileyo ekhuselekileyo ekukhanyeni.
KuSetyenziso lweMfuyo kuphela, Gcina kwindawo engafikelelekiyo ebantwaneni
